Wearing coloured contacts? Start with the exact variant, because the red Vita Clear Cool and yellow W Care cannot be used while coloured or circle lenses are in your eyes. For dryness, the three CL-s versions and two Ice versions are the relevant group; for fatigue or itching, the formulas change. A higher cooling number is a sensation rating, not a treatment ranking.

I'm Irene, a Taiwan-born pharmacist licensed in Japan, currently working in a Japanese drugstore. With similarly named eye drops, I like to make the first decision simple: check your lenses and your main symptom before choosing a colour.
Source check: 14 October 2026 (Japan time). This guide covers the seven Japanese New Mytear CL variants listed below, all 15 mL, Class 3 OTC medicines. Check the full name on the pack, including its suffix, so you pick the version compared here.
A quick way to narrow the choice
- Dryness or contact-lens discomfort: compare CL-s, Cool-s and Cool Hi-s first if you want the same active formula with different cooling sensations.
- Prefer a strongly cooling dryness formula: Ice Crush and Ice Refresh have different active ingredients from the CL-s trio and from each other.
- Eye fatigue without coloured lenses in place: Vita Clear Cool is the fatigue-focused formula.
- Itching plus fatigue without coloured lenses in place: W Care contains an antihistamine. Persistent itch still needs assessment.
- Severe eye pain, ongoing blurred vision or an eye under medical treatment: get professional advice rather than experimenting with stronger cooling.
Seven packs, three practical decisions
The table compares one 15 mL product of each type. Cooling numbers use Senju’s 0–10 scale and describe sensation only. All seven labels direct 2–3 drops per application, 5–6 times daily; children require adult supervision, and the leaflets do not establish a numerical minimum age. The coloured-lens “yes” applies only to lenses approved in Japan as specially controlled medical devices, including circle lenses.
| Variant / Japanese shelf name | Cooling | Main label-based distinction | Coloured lenses in place |
|---|---|---|---|
| CL-s / CL-s | 0 | Dryness; same actives as the next two | Yes, with the qualification above |
| Cool-s / CLクール-s | 2 | Same actives, mild cooling | Yes, with the qualification above |
| Cool Hi-s / CLクールHi-s | 7 | Same actives, strong cooling | Yes, with the qualification above |
| Ice Crush / CLアイスクラッシュ | 10 | Dryness formula with chondroitin | Yes, with the qualification above |
| Ice Refresh / CLアイスリフレッシュ | 8 | Dryness formula with potassium L-aspartate | Yes, with the qualification above |
| Vita Clear Cool / CLビタクリアクール | 7 | Fatigue formula with B6, B12 and neostigmine | No |
| W Care / CL-Wケア | 6 | Itching and fatigue; contains chlorpheniramine | No |







The formulas are not one cooling ladder
Every quantity below is an active-ingredient amount per 1 mL of solution, not per drop or daily dose. Larger numbers do not prove that a product works better.
| Formula | All active ingredients per 1 mL |
|---|---|
| CL-s / Cool-s / Cool Hi-s | Sodium chloride 5.5 mg; potassium chloride 1.5 mg; glucose 0.05 mg; taurine 1 mg |
| Ice Crush | Sodium chloride 5.5 mg; potassium chloride 1.5 mg; sodium chondroitin sulfate 0.5 mg; glucose 0.05 mg |
| Ice Refresh | Potassium L-aspartate 1 mg; sodium chloride 1 mg; potassium chloride 1 mg |
| Vita Clear Cool | Pyridoxine hydrochloride (B6) 1 mg; cyanocobalamin (B12) 0.2 mg; neostigmine methylsulfate 0.05 mg |
| W Care | Chlorpheniramine maleate 0.3 mg; pyridoxine hydrochloride (B6) 0.1 mg; taurine 1 mg; sodium chondroitin sulfate 5 mg |
The CL-s trio shares its active ingredients, but the additive lists are not identical. Neither the Ice names nor the red liquid mean “a stronger version” of that trio. Vita Clear Cool’s red colour also calls for care around clothing; the leaflet says to wash spills off immediately with water.
Do I need to remove circle lenses for the red or yellow bottle?
Yes: remove coloured or circle lenses before using Vita Clear Cool or W Care. Senju’s product FAQs say reusable lenses may be reinserted after at least five minutes. This does not give permission to reuse daily disposable lenses. All seven may also be used without lenses; ordinary soft and hard lenses are supported as stated on each label. For the first five, check the Japanese approval number on the coloured-lens box rather than assuming every cosmetic lens qualifies.
How to use and when to stop
- Read your exact pack’s leaflet and check lens compatibility. If a child will use it, ask a pharmacist about suitability rather than treating the absence of an age number as permission for babies.
- Use 2–3 drops per application, 5–6 times a day. Do not let the tip touch the eye, eyelid or eyelashes. Do not use cloudy solution.
- Never share the bottle or transfer the contents. Keep it tightly closed, cool, away from sunlight and out of children’s reach; do not leave it in a hot car.
- Use promptly after opening the inner bag. Vita Clear Cool and W Care specify a guideline of within three months; the other five leaflets say promptly without assigning that same number. Never exceed the printed expiry date.
Consult a doctor or pharmacist before use if you are receiving medical treatment, have a history of medicine-related allergy, severe eye pain or glaucoma. Stop immediately and seek advice for rash, skin redness or itching, or eye redness, itching or swelling after use; the CL-s trio also lists irritation. Stop and consult if blurred vision does not improve, or symptoms are no better after about two weeks. The five dryness formulas also specify stopping if heavy discharge clouds hard lenses. These are stop thresholds, not a reason to wait two weeks with severe pain or worsening vision.
For a first pass, remember this order: lens eligibility, main symptom, then cooling preference. You do not need to buy the highest number to make a sensible choice. If the problem keeps returning, checking the cause and lens fit is more useful than building a collection of bottles.
Official sources and image credits
- CL-s: official product page and photograph; Japanese leaflet
- Cool-s: official product page and photograph; Japanese leaflet
- Cool Hi-s: official product page and photograph; Japanese leaflet
- Ice Crush: official product page and photograph; Japanese leaflet
- Ice Refresh: official product page and photograph; Japanese leaflet
- Vita Clear Cool: official product page and photograph; Japanese leaflet
- W Care: official product page and photograph; Japanese leaflet


