I’m Irene, a Taiwan-born, Japan-licensed pharmacist working in a Japanese drugstore. The yellow and orange Selbelle boxes can look similar at first. Let’s separate the formulas first, then choose a form you can take comfortably.
- The quick choice: formula first, tablets or granules second
- Check suitability before choosing a box
- Compare the whole-day amounts, not a single tablet
- Recognize all four current Japanese packs
- All four: after meals, with water or warm water
- When to stop: two weeks is a review point, not a required course
- Three questions before you buy
- Comparing other Japanese stomach medicines?
- Official sources and medical information
The quick choice: formula first, tablets or granules second
Standard Selbelle combines teprenone with two herbal extracts. Premium has a higher daily teprenone amount and adds lipase AP6, an enzyme that helps digest fat. Each formula comes as tablets or fine granules. “Premium” does not mean a better answer to every stomach symptom.
- Comparing the standard formula? Look for the yellow Selbelle Stomach Tablets or Selbelle Fine Granules boxes. Their labeled uses include stomach heaviness and heartburn.
- Interested in an enzyme-containing option for post-meal heaviness? Compare the orange New Selbelle Seii Premium products. Feeling unusually full after a small meal does not, by itself, establish the cause.
- Once you have chosen a formula: choose tablets if that is your usual preference, or single-dose sachets if you prefer granules. Within each formula, the daily active ingredients and amounts match; the inactive ingredients differ.
All four are Class 2 OTC medicines in Japan, for ages 15 and over. This Japanese classification is not a strength rating. The labeled uses overlap substantially, so this is a buying guide rather than a diagnostic test or a plan to combine the products. Check the Japanese pack instead of transferring instructions from a medicine sold in another country.
Check suitability before choosing a box
All four labels say to consult a doctor, pharmacist or registered OTC seller before use if you are receiving medical treatment, pregnant or possibly pregnant, an older adult, have previously had an allergic reaction to a medicine or similar substance, or have diagnosed liver disease. Do not give any of these products to children under 15.
Seek medical assessment for recurring symptoms, significant pain, difficulty swallowing, repeated vomiting or unexplained weight loss. Vomiting blood or material resembling coffee grounds needs immediate medical help; accompanying dizziness, cold clammy skin, abdominal pain or black stools makes this an emergency. Do not wait two weeks to get help for warning signs.
Compare the whole-day amounts, not a single tablet
Every number below is for the adult daily total of 3 tablets or 3 sachets, not one dose. Standard granules total 3 g in three sachets; Premium granules total 2.4 g. The difference in powder weight does not change the number of sachets per dose.
| Active ingredient / role | Standard: tablets and granules | Premium: tablets and granules |
|---|---|---|
| Teprenone / increases gastric mucus | 112.5 mg per day | 150 mg per day |
| Atractylodes lancea rhizome dry extract (ソウジュツ) / supports stomach movement | 150 mg per day Equivalent to 1.5 g of crude herb | 150 mg per day Equivalent to 1.5 g of crude herb |
| Magnolia bark dry extract (コウボク) / supports stomach movement | 83.4 mg per day Equivalent to 1.0 g of crude herb | 83.4 mg per day Equivalent to 1.0 g of crude herb |
| Lipase AP6 / helps digest fat | Not included | 14.7 mg per day |
Gastric mucus helps protect the stomach lining, and teprenone increases this mucus. That is different from neutralizing acid or suppressing acid production. It does not guarantee protection from every cause of stomach injury or replace treatment prescribed for a diagnosed condition.
The four Japanese labels cover stomach heaviness, heartburn, overeating, overdrinking, stomach or abdominal bloating, poor appetite, nausea, vomiting and a sensation of blockage in the chest. They do not list stomach pain or treatment of stomach ulcers as indications. Do not assume unexplained abdominal or chest symptoms are ordinary indigestion.
Both granule formulas list cinnamon bark (ケイヒ), lactose, menthol and peppermint oil as inactive ingredients. Cinnamon is not one of the active ingredients in the table. If you have an allergy history or a concern about an excipient, show the complete ingredient list to a pharmacist rather than assuming tablets and granules are identical in every respect.
Recognize all four current Japanese packs
Use yellow versus orange as a first clue, then read the full name and the form: 錠 means tablets and 細粒 means fine granules. Eisai says all four packs are undergoing a gradual packaging change with no ingredient change. Older-looking and newer-looking boxes may therefore coexist in shops. The images below are the current official display images; the pack sizes shown are identification examples.
1. Standard tablets: セルベール整胃錠
Look for 整胃錠 at the end of the name. The dose is one tablet, three times daily. Officially listed sizes are 12, 21 and 45 tablets; a larger pack is not a different formula or a recommended course length.
2. Standard fine granules: セルベール（細粒）
One dose is one 1 g sachet. The daily active ingredients and amounts match standard tablets, making this the standard-formula option for people who prefer premeasured granules. Officially listed sizes are 12 and 27 sachets.
3. Premium tablets: 新セルベール整胃プレミアム＜錠＞
Check for both プレミアム and 錠. The dose is still one tablet, not a larger dose because the label says Premium. Officially listed sizes are 18, 36 and 72 tablets.
4. Premium fine granules: 新セルベール整胃プレミアム＜細粒＞
One dose is one 0.8 g sachet. Daily active ingredients and amounts match Premium tablets. Officially listed sizes are 12 and 24 sachets. A smaller powder weight still provides the full labeled dose.
All four: after meals, with water or warm water
For ages 15 and over, take one tablet or one sachet per dose, three times daily after meals, with water or warm water. Choose the instructions for your form. None of the four is for children under 15; do not improvise a half-dose for a child.
1 tablet or 1 sachet
With water / warm water
1 tablet or 1 sachet
With water / warm water
1 tablet or 1 sachet
With water / warm water
This illustrates three doses of one selected product, not four products at each meal. Easy-dissolving granules still require water or warm water. The tablets are not labeled as chewables. Do not take the entire daily amount at once or add another form as an extra dose.
For travel, keep the original packaging and leaflet, store it in a cool, dry place away from direct sunlight and out of children’s reach. Do not use expired medicine. Close tablet bottles firmly and avoid handling tablets with wet hands. The standard 21- and 45-tablet bottles and Premium tablet bottles have a six-month-after-opening use guideline, always within the printed expiry date. This is a storage limit, not advice to take the medicine for six months.
When to stop: two weeks is a review point, not a required course
If symptoms have not improved after about two weeks, stop and take the leaflet to a doctor, pharmacist or registered OTC seller. All four labels give this instruction. Get help sooner for worsening symptoms or warning signs; switching boxes does not reset the clock.
- Stop immediately and consult: rash, redness, itching, abdominal bloating, nausea, abdominal pain, headache or bleeding under the skin / unexplained bruising after taking the medicine.
- Stop and consult if these persist or worsen: constipation, diarrhea or dry mouth.
- Rare liver dysfunction needs immediate medical care: possible signs include fever, itching, rash, yellow skin or eyes, brown urine, general tiredness and loss of appetite. Do not wait for every sign to appear.
Three questions before you buy
Does more teprenone make Premium the better choice?
The labels establish ingredient amounts and the added fat-digesting enzyme, not which formula will work best for every person. Uses overlap, and repeated post-meal discomfort can have different causes. Check suitability first, then compare formula, form and inactive ingredients.
Can I take it preventively, or automatically add it to a painkiller?
Do not make these products a symptom-free daily routine or automatically pair them with every painkiller, cold medicine or antibiotic. Ask a pharmacist or doctor to check the exact medicines. Increasing gastric mucus does not guarantee prevention of medicine-related stomach injury. People receiving medical treatment are already in the labels’ pre-use consultation group.
Is the standard formula automatically suitable in pregnancy or breastfeeding?
Pregnancy or possible pregnancy requires consultation for all four. Choosing standard does not remove that step. If breastfeeding, discuss your individual medicine choice with a doctor or pharmacist too. The Japanese inserts do not specifically prohibit use while breastfeeding, but that does not establish suitability for every breastfeeding person.
Comparing other Japanese stomach medicines?
The separate guides to Cabagin α Plus tablets and granules, Sucrate G, standard and S products, and the three Gaster10 forms explain those products’ own formulas, restrictions and dosing times. They are further reading, not a suggestion to combine treatments.
Bring a pack photo, a note of how long symptoms have lasted, and a list of medicines you already take. That gives the pharmacist much more to work with than a request for a “stronger stomach medicine.”
Official sources and medical information
- Eisai：Standard Selbelle tablets product information · Japanese package insert
- Eisai：Standard Selbelle fine granules product information · Japanese package insert
- Eisai：New Selbelle Seii Premium tablets product information · Japanese package insert
- Eisai：New Selbelle Seii Premium fine granules product information · Japanese package insert
- NHS：indigestion and when to seek care · vomiting blood
Information checked: 18 October 2026. This guide covers the Japanese products and provides general buying and use information, not an individual diagnosis. Read the leaflet supplied with your medicine. Product images: Eisai; copyright remains with the owner.
